CA 72-4 is found on the surface of cancer cells and belongs to the mucin family. CA 72-4 is a tumor marker glycoprotein, which increases in variety of human adenocarcinomas such as gastric, colon, breast, and ovarian cancer. Also, the positive rate of CA 72-4 is significantly higher in the cases with lymph node metastasis. The combination of CA 72-4 with other known serum cancer markers, such as CEA and CA 19-9 (for gastrointestinal cancer) or CA 125 (for ovarian cancer), indicated that an increase in the sensitivity can be achieved without substantial changes in the overall specificity, improving the possibility of monitoring these cancerous patients. CA 72-4 is used as a positive control in various immunoassays (like ELISA, ECLIA) for the detection of variety of cancers.
Gastrointestinal & Gynaecological Cancer Antigen CA 72-4 (Partially Pure)
Product Code : 00-AGN-TM-0CA-003
Specifications:
| Parameters | Acceptance Criteria |
|---|---|
| Physical Appearance | Colourless to pale yellow liquid |
| CA 72-4 Concentration By Roche Cobas (ECLIA) |
≥ 10 KU/ml |
| Contaminants By Roche Cobas (ECLIA) |
CA 125, CEA, CA 19-9, CA 15-3, AFP, Ferritin concentrations should be ≤ 25% of CA 72-4 concentration (On Roche Cobas) |
| Form | Liquid |
| Storage buffer | Phosphate buffer saline with 0.1% NaN3, pH 7.4 ± 0.2 |
| Storage temperature | 2 to 8˚C |
| Shelf life | 2 years |
| Anti HIV1&2 (ELISA) | Negative |
| Anti HCV (ELISA) | Negative |
| HBsAg Antigen (ELISA) | Negative |
| HBV DNA (PCR) | Not detected |
| HCV RNA (PCR) | Not detected |
| HIV DNA (PCR) | Not detected |
| Source of the product | Human ascitic fluid |
For research use or further manufacturing purposes only