Immunoglobulin M (IgM) is the first and the largest antibody produced in response to an antigen. IgM is involved in complement activation, therefore leading to opsonization of antigens and cytolysis. Anti-Human IgM serum is used in various ELISA and immunohistochemistry assays. The presence of IgM antibodies in a patient’s serum indicates recent infection, or in case of a neonate’s serum, indicates intrauterine infection. Anti-Human IgM is used in the development and manufacturing of various qualitative and quantitative assays based on RID, IEP, ELISA, latex enhanced immunoturbidimetric assays, ouchterlony double diffusion, western blot, and precipitin assay.
Anti-Human IgM
Product Code : 00-ABD-MM-IgM-001, 00-ABD-MM-IgM-002
Available products:
Product Name (New) | Product Code | Grade |
---|---|---|
Goat Anti-Human IgM, Whole Serum | 00-ABD-MM-IgM-001 | Whole Serum |
Goat Anti-Human IgM, Fractionated | 00-ABD-MM-IgM-002 | Fractionated |
Specifications:
Test parameters | Acceptance Criteria |
---|---|
Product Code | 00-ABD-MM-IgM-001 |
Host | Goat |
Immunogen | Human IgM-µ chain |
Grade | Whole Serum |
Physical Appearance | Straw to brownish yellow clear liquid without any suspended particles |
Titre (Reverse Single Radial Immunodiffusion) | > 8 mg/ml |
Shelf life | 3 years |
Buffer details* | Tris Saline with 15mM NaN3, pH 7.4 ± 0.2 |
Total Protein (Biuret Method) | 50 to 140 mg/ml |
Cholesterol (CHOD Enzymatic method) | ≤50 mg/dl |
Specificity (Immunoelectrophoresis) | Monospecific to IgM when reacted with normal human serum |
pH | 7.0 to 8.0 |
Storage conditions | 2 to 8ºC |
Test parameters | Acceptance Criteria |
---|---|
Product Code | 00-ABD-MM-IgM-002 |
Host | Goat |
Immunogen | Human IgM-µ chain |
Grade | Fractionated |
Physical Appearance | Clear, off white to Pale yellow liquid without any suspended particles |
Titre (Reverse Single Radial Immunodiffusion) | > 8 mg/ml |
Shelf life | 3 years |
Buffer details* | Saline with 15mM NaN3 |
Total Protein (Biuret Method) | 25 to 150 mg/ml (Biuret); > 60 mg/ml (OD at 280nm) |
Specificity (Immunoelectrophoresis) | Monospecific to IgM when reacted with normal human serum |
pH | 7.0 to 8.0 |
Storage conditions | 2 to 8ºC |
*Buffer composition can be customised as per the customer requirements. Product can be further customised as per the specific requirements.
For research use or further manufacturing purposes only