Bence Jones proteins are immunoglobulin light chains that are present in urine because of decreased kidney filtration capabilities due to renal failure. It is used in the diagnosis of multiple myeloma, and also as a calibrator in various in vitro diagnostic kits. It’s mainly used as a renal marker and as controls and calibrators in qualitative and quantitative turbidimetric, ELISA and CLIA, ECLIA, CMIA assays. It can be used in radial immunodiffusion, immunoelectrophoresis, western blotting, dot blot, and other similar assays. It can be used in the development of target-specific assay reagents and also used for cancer research and development. It’s also used as an immunogen to raise antibodies in animals.
Bence Jones Protein Kappa Free Light Chain
Product Code : 00-AGN-TM-BJK-001
Specifications:
| Parameters | Acceptance Criteria |
|---|---|
| Physical Appearance | Colourless to pale yellow liquid |
| Concentration | ≥ 1.0 mg/ml (By Immunoturbidimetry method) |
| % Purity (SDS PAGE) | ≥98 % |
| Cross-contaminants | ≤ 1%: Lambda free light chain, IgG, IgM, IgA, Cystatin-C and Microalbumin |
| Formulation | Liquid |
| Storage buffer | Phosphate buffer saline with 0.1% NaN3 pH 7.4 ± 0.2 |
| Storage temperature | 2 to 8˚C |
| Shelf life | 1.5 years |
| Anti HIV1&2 (ELISA) | Negative |
| Anti HCV (ELISA) | Negative |
| HBsAg Antigen (ELISA) | Negative |
| HIV Ag (PCR) | Not detected |
| Syphilis | Not detected |
| Source of the product | Human renal failure patient pooled urine |
For research use or further manufacturing purposes only